Leptin levels are associated with multiple sclerosis risk

ECTRIMS 2019 | Best Practice Nordic | 13. Sep 2019 kl. 10:13 |

Overweight, including obesity, early in life has been linked to increased risk of developing MS. The link between obesity and MS could be the adipokine leptin because leptin is strongly correlated to both body mass index and total fat mass. Clich and hear Martin Biström gives you the answer about the possible ...

Impact of age on treatment decisions

ECTRIMS 2019 | Best Practice Nordic | 12. Sep 2019 kl. 10:11 |

Higher age is associated with quantitative and functional changes in the innate and adaptive immune system, and an age dependent reduction in efficacy of disease modifying therapies. In this MEDtalk Per Soelberg Sørensen present data that shows, that the choice of initial disease modifying therapies differs according to the age of the patient. Fewer patients ...

Acute disseminated encephalomyelitis (ADEM) can cause cognitive impairment in children. However, long-term consequences for school performance and psychiatric morbidity have never been characterized. In this study Magnus Spangsberg Boesen investigate long-term school performance and psychiatric morbidity after paediatric ADEM. Click and hear the interesting ...

In this MEDtalk Line Jørgensen explaine why the data from her study indicate a potential alternative mechanism of cladribine with direct effect on CNS resident ...

This is the first Neuromyelitis optica spectrum disorder study reporting the effects of migration on the outcomes in different ...

Pregnancy in MS women with recent relapses (during the year prior to conception) increases the risk of long-term disability ...

In a previous study on pregnancy in multiple sclerosis (MS) women treated with natalizumab, the combination of avoiding natalizumab wash-out and the early resumption of treatment after delivery represented the best option in the perspective of maternal risk. This study is a re-appraisal of maternal outcomes in the same cohort of women after a six-year ...

Profiling epigenetic changes may open promising insights into the PPMS pathogenesis and provide novel biomarkers and therapeutic approaches. Click and hear ...

The incidence of epilepsy is increased in multiple sclerosis (MS) but its impact on MS prognosis is largely unknown. In this MEDtalk Zamzam Mahamud present data show the the effect of epilepsy diagnosis on the risk of conversion to secondary progressive MS and mortality. The data suggesting that epilepsy could be a marker for severe ...

Natalizumab usage in Denmark

ECTRIMS 2019 | Best Practice Nordic | kl. 4:45 |

This study reports that natalizumab treatment has been broadly employed and usage appears to be in accordance with the approved indication in Europe. Natalizumab treatment termination typically results from JC virus status or anti-natalizumab antibodies and very infrequently due to lack of efficacy and adverse events. Most treatment switches from natalizumab are to other high-efficacy ...

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BestPractice Nordic

Nr. 2 • juni 2020
1. Årgang
  • Diabetes type 2 og hjertesykdom
  • Pneumokokkvaksinering
  • Prevensjon