Cardiotoxicity in BRAF/MEK-Treated Melanoma: A Manageable but Underrecognized Risk
BRAF/MEK inhibitors improve survival in metastatic melanoma but carry a significant risk of cardiotoxicity. Our real-world study found a 21% incidence of LVEF-reduction in a Danish patient cohort, primarily within the first year. Most cases were reversible, underscoring the need for monitoring and individualized management.
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